DMRforPairs output generated on Sun Jul 10 23:23:41 2022. Identified regions were set to contain at least 4 probes with a maximum distance of 200 bp between individual probes (n=28713). Regions in which median methylation levels (M-values) between the samples differed at least |1.4| (n=134) (=relevant) were tested for statistical significance (significant: p<0.05; multiple testing adjusted, n=79). The folowing samples were studied: A98.M,A99.M. Chromosomal positions are indicated in bp. N indicates the number of probes in a region. ID indicates the region ID. Values in the columns per sample indicate median beta values. dM indicates the largest median difference (absolute) between any of the sample pairs. p indicates uncorrected p-value from Mann-Whitney U test (n=2) or Kruskal Wallis test (n>2). p.adj denotes the multiple testing corrected p-value (method:fdr). Gene symbols of overlapping transcripts are listed for the exact region and within a margin of 10000 bp of the region.
Thumbnail Chr Start End Links Length n ID Class A98.beta A99.beta Gene.Symbol dM p p.adj
6 136847695 136847788 PDF
STATS
ENSEMBL
UCSC
94 4 33388 gene;tss 0.5068 0.0872 MAP7 (margin: MAP7; 7SK; RP3-325F22.5) 3.34 0.0285714 0.04846
11 46383031 46383209 PDF
STATS
ENSEMBL
UCSC
179 4 5880 gene 0.4741 0.0948 DGKZ (margin: DGKZ; MIR4688; MDK; CHRM4) 3.10 0.0285714 0.04846
19 16178420 16178570 PDF
STATS
ENSEMBL
UCSC
151 4 19391 gene 0.3614 0.8058 CTD-2231E14.4; TPM4 (margin: CTD-2231E14.4; TPM4; LINC00905; OR1AB1P) 2.85 0.0285714 0.04846
19 18723491 18723596 PDF
STATS
ENSEMBL
UCSC
106 5 20105 tss 0.1038 0.3521 TMEM59L; CRLF1 (margin: C19orf60; TMEM59L; CRLF1; KLHL26; RN7SL155P) 2.80 0.0079365 0.02659
7 70252335 70252662 PDF
STATS
ENSEMBL
UCSC
328 4 35517 gene;island 0.7579 0.3317 AUTS2 (margin: AUTS2) 2.72 0.0285714 0.04846
19 18118800 18118880 PDF
STATS
ENSEMBL
UCSC
81 4 20088 tss 0.0691 0.2701 KCNN1; ARRDC2 (margin: KCNN1; ARRDC2; CTB-52I2.4) 2.64 0.0285714 0.04846
20 36793705 36793747 PDF
STATS
ENSEMBL
UCSC
43 4 24984 tss 0.0590 0.2841 TGM2 (margin: TGM2) 2.60 0.0285714 0.04846
1 223317256 223317548 PDF
STATS
ENSEMBL
UCSC
293 5 2106 tss;island 0.5940 0.1910 RP11-239E10.2; TLR5 (margin: RP11-239E10.2; TLR5) 2.59 0.0079365 0.02659
10 123353298 123353578 PDF
STATS
ENSEMBL
UCSC
281 6 4329 gene;island 0.8505 0.4725 FGFR2 (margin: FGFR2; RP11-62L18.3) 2.58 0.0021645 0.01735
20 36793614 36793747 PDF
STATS
ENSEMBL
UCSC
134 5 25433 island 0.0660 0.2853 TGM2 (margin: TGM2) 2.51 0.0079365 0.02659
15 29562049 29562223 PDF
STATS
ENSEMBL
UCSC
175 4 12374 gene;tss;island 0.3642 0.0992 NDNL2 (margin: FAM189A1; NDNL2) 2.47 0.0285714 0.04846
19 18118800 18119064 PDF
STATS
ENSEMBL
UCSC
265 5 19413 gene;island 0.0808 0.2509 KCNN1; ARRDC2 (margin: KCNN1; ARRDC2; CTB-52I2.4) 2.39 0.0079365 0.02659
16 85517170 85517684 PDF
STATS
ENSEMBL
UCSC
515 7 15674 island 0.7307 0.3593 (margin: ) 2.37 0.0023310 0.01735
1 147012719 147013221 PDF
STATS
ENSEMBL
UCSC
503 8 1697 tss 0.4435 0.1130 BCL9 (margin: BCL9; LINC00624) 2.33 0.0281274 0.04846
3 124103560 124103696 PDF
STATS
ENSEMBL
UCSC
137 4 27401 gene 0.8446 0.5264 KALRN (margin: KALRN; RNU6-143P) 2.28 0.0285714 0.04846
6 43251710 43252017 PDF
STATS
ENSEMBL
UCSC
308 4 33263 gene;island 0.5280 0.8351 TTBK1 (margin: TTBK1; SLC22A7; RP11-480N24.3; CRIP3; ZNF318) 2.26 0.0285714 0.04846
12 52626814 52627047 PDF
STATS
ENSEMBL
UCSC
234 5 9625 island 0.1858 0.5616 LINC00592; KRT7; METTL7AP1 (margin: LINC00592; KRT7; METTL7AP1; KRT86; C12orf80; RP3-416H24.1; KRT121P) 2.10 0.0079365 0.02659
14 70345898 70346096 PDF
STATS
ENSEMBL
UCSC
199 7 11546 tss 0.1287 0.3985 SMOC1; RPL7AP6 (margin: SMOC1; RPL7AP6) 2.06 0.0040793 0.02485
19 18723491 18723685 PDF
STATS
ENSEMBL
UCSC
195 6 21232 island 0.1187 0.4104 TMEM59L; CRLF1 (margin: C19orf60; TMEM59L; CRLF1; KLHL26; RN7SL155P) 2.05 0.0259740 0.04846
12 54070114 54070610 PDF
STATS
ENSEMBL
UCSC
497 10 8915 tss 0.0538 0.2287 ATP5G2 (margin: ATP5G2) 2.05 0.0185434 0.04846
11 124492411 124492734 PDF
STATS
ENSEMBL
UCSC
324 7 6989 tss 0.1950 0.0550 PANX3; TBRG1 (margin: PANX3; TBRG1; OR8Q1P; RNA5SP352; SIAE) 2.03 0.0023310 0.01735
12 52626814 52626904 PDF
STATS
ENSEMBL
UCSC
91 4 8891 tss 0.2067 0.5134 LINC00592; KRT7; METTL7AP1 (margin: LINC00592; KRT7; METTL7AP1; KRT86; C12orf80; RP3-416H24.1; KRT121P) 2.02 0.0285714 0.04846
6 29523786 29524117 PDF
STATS
ENSEMBL
UCSC
332 6 32791 gene;island 0.4668 0.7388 GABBR1; OR2I1P; UBD (margin: GABBR1; RPL13AP; OR2I1P; UBD; LINC01015; OR2H5P; TMEM183AP1; SNORD32B; GPR53P) 2.01 0.0021645 0.01735
5 37834909 37835168 PDF
STATS
ENSEMBL
UCSC
260 7 31358 tss 0.2110 0.5304 GDNF-AS1; GDNF (margin: GDNF-AS1; GDNF) 2.00 0.0005828 0.00976
20 56265687 56266295 PDF
STATS
ENSEMBL
UCSC
609 8 24707 gene;tss 0.7378 0.4886 PMEPA1 (margin: PMEPA1) 1.99 0.0029526 0.01884
1 38512518 38512851 PDF
STATS
ENSEMBL
UCSC
334 5 1322 tss;island 0.1554 0.3500 RP5-884C9.2; POU3F1 (margin: UTP11L; RP5-884C9.2; POU3F1) 1.95 0.0079365 0.02659
5 37834672 37835168 PDF
STATS
ENSEMBL
UCSC
497 10 30932 gene;island 0.1943 0.4981 GDNF-AS1; GDNF (margin: GDNF-AS1; GDNF) 1.95 0.0000433 0.00508
3 16926159 16926350 PDF
STATS
ENSEMBL
UCSC
192 6 27672 tss;island 0.2034 0.0674 PLCL2 (margin: PLCL2) 1.89 0.0086580 0.02762
20 23066999 23067159 PDF
STATS
ENSEMBL
UCSC
161 5 24887 tss 0.3500 0.1276 CD93; AL118508.1 (margin: CD93; AL118508.1) 1.88 0.0079365 0.02659
10 105452885 105453461 PDF
STATS
ENSEMBL
UCSC
577 8 4293 gene;island 0.1795 0.4329 SH3PXD2A (margin: SH3PXD2A; Y_RNA) 1.87 0.0029526 0.01884
11 124492411 124492831 PDF
STATS
ENSEMBL
UCSC
421 9 8016 island 0.1784 0.0550 PANX3; TBRG1 (margin: PANX3; TBRG1; OR8Q1P; RNA5SP352; SIAE) 1.87 0.0004936 0.00976
5 159343148 159343549 PDF
STATS
ENSEMBL
UCSC
402 5 31745 tss;island 0.3049 0.1198 ADRA1B (margin: ADRA1B) 1.86 0.0079365 0.02659
22 45725485 45725705 PDF
STATS
ENSEMBL
UCSC
221 4 26290 gene 0.7431 0.4545 FAM118A (margin: FAM118A; SMC1B) 1.80 0.0285714 0.04846
22 45608345 45608713 PDF
STATS
ENSEMBL
UCSC
369 10 26288 gene 0.3357 0.6653 KIAA0930 (margin: KIAA0930; NUP50; MIR1249) 1.79 0.0000758 0.00508
14 103989208 103989789 PDF
STATS
ENSEMBL
UCSC
582 10 11727 tss 0.1199 0.3415 TRMT61A; CKB; RP11-600F24.7 (margin: MARK3; TRMT61A; RNU7-160P; RP11-894P9.2; CKB; RP11-600F24.7) 1.78 0.0015047 0.01735
13 21900392 21900591 PDF
STATS
ENSEMBL
UCSC
200 4 10691 island 0.2236 0.4919 GRK6P1; LINC00422 (margin: MIPEPP3; GRK6P1; LINC00422) 1.78 0.0285714 0.04846
7 112120730 112121036 PDF
STATS
ENSEMBL
UCSC
307 7 36208 tss 0.6992 0.4095 IFRD1; LSMEM1 (margin: IFRD1; LSMEM1) 1.74 0.0023310 0.01735
17 73583839 73584111 PDF
STATS
ENSEMBL
UCSC
273 7 17224 tss;island 0.1419 0.3075 MYO15B (margin: MYO15B; LLGL2) 1.72 0.0005828 0.00976
17 75315486 75315868 PDF
STATS
ENSEMBL
UCSC
383 9 16341 gene 0.0760 0.1922 SEPT9 (margin: SEPT9) 1.72 0.0027561 0.01884
16 20085100 20085358 PDF
STATS
ENSEMBL
UCSC
259 5 14452 tss 0.2621 0.0892 GPR139 (margin: GPR139) 1.71 0.0158730 0.04525
2 152956034 152956135 PDF
STATS
ENSEMBL
UCSC
102 4 23023 tss;island 0.3677 0.1353 AC079790.2; CACNB4 (margin: AC079790.2; CACNB4; STAM2) 1.71 0.0285714 0.04846
1 35226707 35227272 PDF
STATS
ENSEMBL
UCSC
566 4 311 gene;island 0.7799 0.4980 GJB5; GJB4; RP1-34M23.5 (margin: GJB5; GJB4; RP1-34M23.5; GJB3; AL121988.1) 1.70 0.0285714 0.04846
14 90042201 90042373 PDF
STATS
ENSEMBL
UCSC
173 5 11217 gene;tss 0.6641 0.8534 FOXN3-AS2; Y_RNA (margin: FOXN3-AS2; Y_RNA) 1.69 0.0079365 0.02659
14 103989189 103989789 PDF
STATS
ENSEMBL
UCSC
601 11 12289 island 0.1138 0.3368 TRMT61A; CKB; RP11-600F24.7 (margin: MARK3; TRMT61A; RNU7-160P; RP11-894P9.2; CKB; RP11-600F24.7) 1.68 0.0007655 0.01140
17 40439628 40439765 PDF
STATS
ENSEMBL
UCSC
138 5 16113 gene 0.1061 0.2660 STAT5A (margin: STAT5A; RP11-358B23.5; STAT5B; AC003104.1; STAT3) 1.66 0.0079365 0.02659
3 62304470 62304779 PDF
STATS
ENSEMBL
UCSC
310 7 27939 tss;island 0.1634 0.0724 C3orf14; PTPRG-AS1 (margin: PTPRG; C3orf14; PTPRG-AS1) 1.62 0.0005828 0.00976
12 89748726 89749080 PDF
STATS
ENSEMBL
UCSC
355 6 9852 island 0.5596 0.7866 DUSP6 (margin: DUSP6; RP11-1109F11.3; RP11-1109F11.5) 1.60 0.0259740 0.04846
20 23012142 23012241 PDF
STATS
ENSEMBL
UCSC
100 4 25316 island 0.7893 0.5745 RP4-753D10.3; SSTR4; RP4-753D10.5 (margin: THBD; RP4-753D10.3; SSTR4; RP4-753D10.5) 1.58 0.0285714 0.04846
2 37552111 37552543 PDF
STATS
ENSEMBL
UCSC
433 5 23562 island 0.1566 0.0628 AC007391.2; PRKD3; RNU6-939P (margin: AC007391.2; QPCT; PRKD3; RNU6-939P) 1.57 0.0079365 0.02659
22 45608428 45608713 PDF
STATS
ENSEMBL
UCSC
286 9 26634 tss 0.3382 0.6628 KIAA0930 (margin: KIAA0930; NUP50; MIR1249) 1.57 0.0002879 0.00965
3 186646931 186647026 PDF
STATS
ENSEMBL
UCSC
96 4 28291 tss;island 0.5551 0.3234 ST6GAL1; AC007690.1; RP11-42D20.1 (margin: ST6GAL1; AC007690.1; RP11-42D20.1; RPS20P14) 1.56 0.0285714 0.04846
17 75315486 75315567 PDF
STATS
ENSEMBL
UCSC
82 6 17266 tss 0.0676 0.1701 SEPT9 (margin: SEPT9) 1.55 0.0021645 0.01735
4 779480 779880 PDF
STATS
ENSEMBL
UCSC
401 4 29328 gene;island 0.4571 0.6740 RP11-440L14.1; CPLX1 (margin: PCGF3; RP11-440L14.4; RP11-440L14.1; AC139887.4; CPLX1) 1.55 0.0285714 0.04846
3 179754521 179754761 PDF
STATS
ENSEMBL
UCSC
241 6 28253 tss;island 0.2017 0.0756 PEX5L (margin: PEX5L) 1.55 0.0086580 0.02762
2 74731354 74731413 PDF
STATS
ENSEMBL
UCSC
60 4 22160 gene;tss;island 0.3735 0.6029 RP11-523H20.3; LBX2-AS1; TLX2; LBX2; AC005041.17; PCGF1; TTC31 (margin: RP11-523H20.3; LBX2-AS1; TLX2; LBX2; AC005041.17; PCGF1; DQX1; TTC31; HTRA2; CCDC142; AUP1; LOXL3) 1.53 0.0285714 0.04846
1 156786601 156786723 PDF
STATS
ENSEMBL
UCSC
123 7 689 gene;tss;island 0.3009 0.1287 NTRK1; SH2D2A (margin: NTRK1; SH2D2A; PRCC; INSRR) 1.53 0.0262238 0.04846
3 33701101 33701223 PDF
STATS
ENSEMBL
UCSC
123 5 27158 gene 0.7158 0.4887 CLASP2 (margin: CLASP2) 1.52 0.0079365 0.02659
7 29234786 29235180 PDF
STATS
ENSEMBL
UCSC
395 5 35453 gene;island 0.2151 0.0729 CHN2; CPVL; AC004593.3 (margin: CHN2; NANOGP4; CPVL; AC004593.3) 1.51 0.0079365 0.02659
14 23834860 23834995 PDF
STATS
ENSEMBL
UCSC
136 6 11363 tss 0.2314 0.4795 RP11-124D2.3; IL25; EFS (margin: RP11-124D2.3; IL25; CMTM5; SLC22A17; EFS; MYH6; MIR208A) 1.50 0.0043290 0.02522
14 23834808 23834995 PDF
STATS
ENSEMBL
UCSC
188 7 11802 island 0.1977 0.4614 RP11-124D2.3; IL25; EFS (margin: RP11-124D2.3; IL25; CMTM5; SLC22A17; EFS; MYH6; MIR208A) 1.49 0.0110723 0.03297
8 104153592 104153753 PDF
STATS
ENSEMBL
UCSC
162 5 37511 gene;tss;island 0.6902 0.4051 KB-1639H6.4; BAALC; C8orf56 (margin: KB-1639H6.4; BAALC; MIR3151; C8orf56; RP11-318M2.2) 1.48 0.0079365 0.02659
11 86383182 86383585 PDF
STATS
ENSEMBL
UCSC
404 10 6136 gene 0.2043 0.0764 ME3 (margin: ME3) 1.48 0.0002057 0.00919
2 101593139 101593460 PDF
STATS
ENSEMBL
UCSC
322 4 22221 gene 0.6101 0.3975 NPAS2; AC016738.3 (margin: NPAS2; RPL31; AC016738.3; AC016738.4) 1.47 0.0285714 0.04846
1 1602481 1603013 PDF
STATS
ENSEMBL
UCSC
533 7 38 gene;island 0.8449 0.6500 RP11-345P4.10; SLC35E2B; RP11-345P4.7; RP11-345P4.6 (margin: CDK11B; RP11-345P4.10; SLC35E2B; RP11-345P4.7; RP11-345P4.6; MMP23A) 1.47 0.0069930 0.02659
14 94393497 94393816 PDF
STATS
ENSEMBL
UCSC
320 7 11244 gene;tss 0.7581 0.5212 FAM181A; FAM181A-AS1; ASB2 (margin: FAM181A; FAM181A-AS1; ASB2; RP11-131H24.4; MIR4506) 1.46 0.0069930 0.02659
7 28997781 28998009 PDF
STATS
ENSEMBL
UCSC
229 4 35450 gene 0.1222 0.2772 AC005013.5; AC005013.1; TRIL (margin: AC005013.5; CTB-113D17.1; AC005162.5; AC005013.1; TRIL) 1.46 0.0285714 0.04846
3 134083080 134083286 PDF
STATS
ENSEMBL
UCSC
207 4 27438 gene;island 0.1437 0.2800 AMOTL2; RPL39P5 (margin: HMGN1P9; RP11-375I20.6; RPL39P5; AMOTL2) 1.45 0.0285714 0.04846
X 14048019 14048281 PDF
STATS
ENSEMBL
UCSC
263 8 40390 island 0.0514 0.0973 GEMIN8 (margin: GEMIN8) 1.44 0.0104118 0.03171
19 1065688 1065860 PDF
STATS
ENSEMBL
UCSC
173 7 19757 tss;island 0.3949 0.6216 ABCA7; HMHA1 (margin: ABCA7; HMHA1; POLR2E; CNN2; AC011558.5) 1.44 0.0023310 0.01735
19 38085456 38085810 PDF
STATS
ENSEMBL
UCSC
355 7 19488 gene;island 0.2357 0.0578 ZNF571-AS1; ZNF540; ZNF571 (margin: ZNF571-AS1; ZNF540; ZNF571; ZFP30) 1.44 0.0011655 0.01562
6 39290342 39290877 PDF
STATS
ENSEMBL
UCSC
536 7 33784 tss 0.5873 0.3226 KCNK17; KCNK16; KIF6 (margin: KCNK17; KCNK16; KIF6) 1.44 0.0174825 0.04846
17 64959947 64960282 PDF
STATS
ENSEMBL
UCSC
336 4 17158 tss;island 0.1487 0.3075 CACNG4 (margin: CACNG4) 1.44 0.0285714 0.04846
10 93390311 93390512 PDF
STATS
ENSEMBL
UCSC
202 4 4221 gene;island 0.5128 0.7289 PPP1R3C (margin: PPP1R3C) 1.43 0.0285714 0.04846
10 135333725 135334061 PDF
STATS
ENSEMBL
UCSC
337 5 5650 island 0.2463 0.1179 RP11-108K14.4; CYP2E1; SPRN; AL161645.2 (margin: RP11-108K14.4; CYP2E1; SPRN; AL161645.1; AL161645.2) 1.43 0.0158730 0.04525
4 1198278 1198478 PDF
STATS
ENSEMBL
UCSC
201 4 29345 gene 0.3906 0.6259 SPON2; CTBP1 (margin: SPON2; CTBP1) 1.42 0.0285714 0.04846
3 46448496 46448963 PDF
STATS
ENSEMBL
UCSC
468 8 27781 tss 0.2477 0.1220 RP11-24F11.2; CCRL2 (margin: LTF; RP11-24F11.2; CCRL2) 1.42 0.0104118 0.03171
19 13030096 13030354 PDF
STATS
ENSEMBL
UCSC
259 5 20008 tss;island 0.2778 0.1155 GCDH; MIR5695; SYCE2; FARSA (margin: GCDH; AD000092.3; MIR5695; CTC-425F1.2; CALR; RAD23A; SYCE2; FARSA; CTC-425F1.4) 1.41 0.0079365 0.02659
17 40439690 40439765 PDF
STATS
ENSEMBL
UCSC
76 4 16924 tss 0.1044 0.2652 STAT5A (margin: STAT5A; RP11-358B23.5; STAT5B; AC003104.1; STAT3) 1.40 0.0285714 0.04846
4 103997887 103998079 PDF
STATS
ENSEMBL
UCSC
193 4 29562 gene;island 0.1019 0.2243 SLC9B2; BDH2 (margin: SLC9B2; BDH2; CENPE) 1.40 0.0285714 0.04846